International Journal of Cancer Research

Objective: To investigate the effect of perioperative blood transfusion on the prognosis of patients undergoing radical surgery for bladder cancer. Methods A retrospective analysis was made of 41 patients who underwent radical resection of bladder cancer, including 27 patients in the perioperative blood transfusion group and 14 patients in the non blood transfusion group. The total survival period, tumor recurrence rate after surgery, lymph node enlargement and metastasis in the operation area and other organ metastasis were compared between the two groups, and prognostic risk factors were analyzed. Results The survival analysis and comparison between the blood transfusion group and the non blood transfusion group showed that the survival period of the patients with bladder cancer undergoing radical surgery in the blood transfusion group was longer than that in the non blood transfusion group（χ2=7.564,P<0.01）. There were differences in prognosis among different blood transfusion volumes (F=4.497, P<0.01). The larger the blood transfusion volume, the worse the prognosis. Conclusion Perioperative blood transfusion is an independent risk factor for the prognosis of bladder cancer patients; The larger the blood transfusion volume, the shorter the total survival time of patients; Its influence is not affected by other factors, which provides reference value for rational blood transfusion and appropriate treatment in clinical practice.

Perioperative blood transfusion; Bladder cancer; Survival analysis; After radical resection