International Journal of Clinical Research

Objective: To investigate the influence of emergency time factors on prognosis of patients with spontaneous intracerebral hemorrhage. Methods: Sixty-seven patients with spontaneous intracerebral hemorrhage of 40-70ml were divided into study group and control group according to the onset time and whether they entered the green channel. There were 30 patients in study group and 37 patients in control group. The study group included patients who arrived at the hospital within 6 hours of onset and activated the stroke green channel, the control group included patients who arrived at the hospita 6 hours after onset and did not activate stroke green channel. Patients in both groups underwent intracranial hematoma removal by stereotactic minimally invasive puncture, and the intracranial pressure was monitored and regulated after surgery. The time factors of pre-hospital emergency care, time factors of in-the hospital emergency care, the postoperative intracranial pressure value, the neurological function deficit score and the postoperative survival of the two groups were compared respectively. Results: There were differences in the time factors of pre-hospital emergency care between the two groups of patients with spontaneous cerebral hemorrhage, the stroke recognition time of the study group was (2.07 ±0.93) hours, compared with the control group (24.38±7.72) hours, the difference was statistically significant (P<0.05),the pre-hospital transport time of the study group was (1.57±0.68) hours, compared with the control group (2.49±0.77) hours, the difference was statistically significant (P<0.05).There were differences in the time factors of in-the hospital emergency care between the two groups of patients with spontaneous cerebral hemorrhage, the time from receiving to starting CT examination in the study group was (14.83±2.67) min, compared with the control group (27.03±6.50) min, the difference was statistically significant (P<0.05), the time of the study group from arriving the hospital ward to the agreeing surgery was (1.37±0.57) hours, compared with the control group (2.81±0.58) hours, the difference was statistically significant (P<0.05), the time of the study group from agreement to puncture was (1.33±0.33) hours, compared with the control group (2.88±0.73) hours, the difference was statistically significant (P<0.05).ICP sensor probe with drainage tube can better detect and regulate intracranial pressure, under the condition that the drainage tube is unblocked, the intracranial pressure is controlled at about 15mmHg, it fluctuates a little. On the third and fourth day after surgery, intracranial pressure in the study group decreased gradually, and the difference was statistically significant compared with the control group (P<0.05).There were statistically significant differences in neurological deficit scores between the study group and the control group at 1 and 2 weeks after admission (P<0.05).The survival rate of patients with spontaneous intracerebral hemorrhage in the study group with short emergency care time factors increased at the 3rd and 6th month, and the difference was statistically significant compared with the control group (P<0.05). Conclusion: The prognosis of intracerebral hemorrhage is positively influenced by the time facrors of pre-hospital emergency care and in-the hospital emergency care, the patients with spontaneous intracerebral hemorrhage who received short emergency care time factors had lower postoperative intracranial pressure, lighter brain damage and better prognosis.

Intracerebral hemorrhare; stroke recognition; pre-hospital emergency care; in-the hospital emergency care; NIHHS