International Journal of Clinical Research

Objective To analyze the effect of metronidazole and cefaclor in the treatment of periodontitis. Methods According to the way of comparative treatment and observation, 68 patients were included in the study. The period was from March 2021 to May 2022. According to the double blind method, they were divided into the control group (34 cases, conventional treatment) and the observation group (34 cases, metronidazole+cefaclor) for treatment. The recovery of the two groups was observed. Results There was no difference in periodontal probing depth, attachment loss and plaque index between the two groups before treatment (P>0.05). After treatment, all indexes in the observation group were lower than those in the control group (P<0.05). The cure time and clinical symptom improvement time of the two groups were compared. The observation group was shorter than the control group (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). Conclusion The clinical treatment of periodontitis patients according to metronidazole+cefaclor can improve the corresponding symptoms of patients, shorten the recovery time of patients, reduce the adverse reactions of patients during the treatment, and have high drug safety.

Metronidazole; Cefaclor; periodontitis