International Journal of Clinical Research

Objective To investigate the treatment and prognosis of neonatal influenza A. Methods Retrospective analysis was conducted on the clinical data of 50 neonatal patients admitted to Zhenping Maternal and Child Health Hospital from January 2019 to March 2020, and the clinical characteristics, clinical examination, treatment and disease outcome of neonatal influenza A were comprehensively analyzed. Results The male to female ratio of 50 children with influenza A was 27:23. There were 32 full-term infants, 18 premature infants and 9 late preterm infants. There were 36 cases in winter and spring, and 14 cases in summer. There were 24 cases of patients who had contact with family members with symptoms such as cold before admission. Clinically, the main symptoms of children are cough, fever, dyspnea, nasal congestion, runny nose, apnea and so on. According to the detection of epidemic virus A antigen, 50 children were positive, 12 children with respiratory syncytial virus positive, 34 children with sputum bacteria culture positive, 32 children with oseltamivir treatment, 4 children with peramivir treatment. According to the selected data, all the children were cured and discharged from hospital, and there was no neonatal death. Conclusion Neonatal influenza A does not show typical symptoms, most of which occur in winter and summer. Most patients recover after recovery, but for some premature infants, serious complications and poor prognosis should be highly vigilant.

Newborn; Influenza A; Clinical features