International Journal of Clinical Research

Objective To investigate the clinical value of CT guided 125I particles in the treatment of malignant tumors. Methods 40 cases of malignant tumors admitted to Lushan County Peoples Hospital from March 2020 to February 2023 were selected as the study subjects, and radioactive 125I particles were implanted under CT guidance. To evaluate the changes of pain indicators at nodes and the short-term therapeutic effect of tumor at different periods such as 24 hours, 3 days, 7 days, 30 days, and 90 days after surgery. Results After using CT to guide the implantation of radioactive 125I particles for treatment, the surgical success rate of patients reached 100%, and compared with pre surgical treatment, the pain numerical scores of patients at various time points after surgical treatment decreased significantly, with a significant difference (P<0.05); The effective rate of pain relief in patients can reach 67.5% after 24 hours of implantation of particles; The effective rates of pain relief were 85%, 82.5%, 77.5%, 77.5%, and 77.5% at various time points 3, 7, 30, and 90 days after surgery, respectively, P<0.05; The short-term efficacy of the patient has been significantly improved after particle implantation treatment. No serious adverse reactions were found after surgery. Conclusion In the clinical treatment of malignant tumor patients, the method of implanting radioactive 125I particles under CT guidance can rapidly and continuously exert the therapeutic effect, and there will be no serious adverse reactions after surgery, which has great clinical promotion value.

Malignant tumor; 125I particles; CT guidance; pain