| Abstract |
Objective: To explore the practical effect of early application of hemofiltration machine for high volume hemofiltration in emergency treatment of severe septic shock. Methods: 96 patients with severe septic shock from April 2022 to March 2023 were randomly divided into two groups: control group (n = 47) and observation group (n = 49). The observation group was given routine emergency nursing mode. Results: The levels of C-reactive protein and procalcitonin were 51.65 ± 5.85 mg/L, 7.52 ± 2.09 mHg/L, which were lower than 126.28 ± 12.30 mg/L, 15.48 ± 3.24 ng/L in the control group; the arterial blood pressure fractional pressure and oxygenation index were 376.71 ± 56.58 mHg, 141.43 ± 29.75 mHg, which were significantly higher than 295.65 ± 35.85 mHg, 104.33 ± 23.34 mHg (p < 0.05) in the control group; before intervention, the APACHE II, MODS scores were 27.01 ± 2.79, 26.95 ± 2.81 and 14.83 ± 1.26, 15.08 ± 1.27 in the control group, which were not statistically significant (p > 0.05) in the control group; after intervention, the APACHE II, APACHE II and APDS scores of the control group were 25.85 ± 2.64, 2094.93 ± 2.93 and 0.34 ± 2.34, and 0.64 ± 0.05 respectively. Conclusion: Early application of high volume hemofiltration in emergency nursing for severe septic shock patients can significantly improve the level of inflammatory factors (calcitonin, C-reactive protein), cardiovascular function (oxygenation index, arterial blood pressure partial pressure) and multiple organ dysfunction.
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