International Journal of Clinical Research

Objective To discuss the effectiveness of liquid based thin layer cytology and colposcopy in clinical pathological examination of gynecological examination. Methods 1500 patients who underwent clinical and pathological examinations in our department from January 2020 to January 2021 were selected to investigate the detection rate of liquid based thin layer cytology and colposcopy. Results By comparing the detection rates between the two groups, it can be seen that in the detection of cervical inflammation disease, 31 cases were detected by colposcopy biopsy, accounting for 15.5%, and 32 cases were detected by liquid based thin layer cytology, accounting for 16.0%. Among them, 32 cases (16.0%) and 30 cases (15.0%) were detected in the invasive cancer groups, respectively. Cervical polyps were detected in 32 cases (16.0%) through colposcopy biopsy, 29 cases (14.5%) through liquid based thin layer cytology, and 96 cases (48.0%) through intraepithelial neoplasia. 80 cases, 40.0%. In terms of detection rate, there were 191 cases of colposcopy biopsy, accounting for 95.5%, while liquid based thin layer cytology examination was only 85.5%. Among them, 11 cases (42.5%) were misdiagnosed and 9 cases (30.0%) were misdiagnosed using colposcopy biopsy, with a diagnostic accuracy of 90.0%. 19 cases (62.5%) were misdiagnosed and 29 cases (32.5%) were missed in liquid based thin-layer cytology examination, with a diagnostic accuracy of 76.0. Vaginoscopy biopsy was better, P<0.05, and the difference was statistically significant. Conclusion The use of colposcopy biopsy for cervical disease patients can effectively detect their condition, have a high detection and diagnostic rate, and provide a foundation for clinical treatment.

Liquid based thin layer cytology examination; Colposcopy examination; Pathological examination