International Journal of Clinical Research

Objective To investigate the appropriate supplemental dose of vitamin D and calcium in pregnant women during pregnancy. Methods From January 2017 to January 2021, a total of 1911 pregnant women in Tiantai County Maternal and Child Health and family Planning Service Center of Taizhou City, Zhejiang Province were selected as the study objects. The blood 25- (OH) D level of pregnant women was detected during 13+6 weeks, 14-20+6 weeks, 21-31+6 weeks and 32 weeks before delivery, and a certain dose of vitamin D and calcium were added according to the determination result of serum 25- (OH) D level of pregnant women. The vitamin D and calcium supplemental dose and dietary sunshine of pregnant women during each pregnancy period were collected. To analyze the relationship between vitamin D and its related influencing factors, and to explore the appropriate dose of vitamin D supplementation with different 25- (OH) D levels in different stages of pregnancy. Results Within 13+6 weeks, vitamin D deficiency and deficiency patients were recommended to supplement 400IU/d and above, and calcium deficiency patients were recommended to supplement 400mg/d and above. During 14 to 20+6 weeks of pregnancy, the minimum supplementation of 800IU/d and above is recommended for insufficient and deficient patients, and the minimum supplementation of 600mg/d and above is recommended for deficient patients. During 21 to 31+6 weeks, the minimum supplementation of 600-400IU/d and above is recommended for normal, insufficient and deficient patients, and the minimum supplementation of 600mg/d and above is recommended for inadequate patients. A minimum supplement of 600IU/d or more is recommended for normal and inadequate patients from 32 weeks to the time before delivery. Conclusion It is recommended to supplement vitamin D and calcium in different doses during different pregnancies, so as to effectively reduce vitamin D deficiency in pregnant women and newborns.

Gynecology; Malignant tumor; Bladder function training; Evidence-based nursing; Clinical effect Gynecology; Malignant tumor; Bladder function training; Evidence-based nursing; Clinical effect