The Omnigenic Model: Implications for Psychiatric Genetics
The Omnigenic Model: Implications for Psychiatric Genetics
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| DOI |
10.20900/jpbs.20170014S1 |
| 刊名 |
JPBS
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| 年,卷(期) |
2017, 2(5) |
| 作者 |
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| 作者单位 |
Department of Psychiatry, SUNY Upstate Medical University
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| Abstract |
Boyle et al omnigenic model posits “core genes” that have “biologically interpretable roles in disease” and many more “peripheral genes” that regulate the activity of the core genes. Because there are many more peripheral genes, they account for a greater proportion of the variability in heritability than do the core genes. Their work is an important milestone for the field inasmuch as it brings into focus many key issues.
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| 基金项目 |
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| 页码 |
- |
Stephen.V.Faraone*.
The Omnigenic Model: Implications for Psychiatric Genetics,
Journal of Psychiatry and Brain Science.
2017; 2; (5).
https://doi.org/10.20900/jpbs.20170014S1.