Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project-Advances in Geriatric Medicine and Research-CSCIED科技核心评价数据库-手机版

Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project

Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project

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DOI	10.20900/agmr20190005
刊名	Advances in Geriatric Medicine and Research AGMR
年，卷(期)	2019, 1(1)
作者	Anna C. Whittaker*,Evans A. Asamane,Justin A. Aunger,Dmitriy Bondarev,Andrea Cabbia,Paul D. Doody,Noémie Gensous,Barbara Iadarola,Keenan A. Ramsey,Belina Rodrigues,Muhammad Rizwan Tahir,Suey S.Y. Yeung,on behalf of the PANINI Consortium,
作者单位	1 School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham B15 2TT, UK; 2 Faculty of Health Sciences and Sport, University of Stirling, Stirling FK9 4LA, Scotland, UK; 3 Gerontology Research Center & Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä 40014, Finland; 4 Department of Biomedical Engineering, Eindhoven University of Technology, Groene Loper, Eindhoven 5612 AP The Netherlands; 5 Department of Experimental, Diagnostic, and Specialty Medicine (DIMES), University of Bologna, Bologna 40126, Italy; 6 Personal Genomics, University of Verona, Via Roveggia 43B, Verona 37136, Italy; 7 Department of Biotechnology, University of Verona, Strada Le Grazie 15, Verona 37134, Italy; 8 Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam 1081 BT, The Netherlands; 9 Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga 4710, Portugal; 10 ICVS/3B's, PT Government Associate Laboratory, Braga/Guimarães 4710, Portugal; 11 Clinical Academic Center-Braga (2CA-B), Braga 4710, Portugal; 12 Department of Microbiology and System Biology, The Netherlands Organisation for Applied Scientific Research, Zeist 3704 HE, The Netherlands
Abstract	Background: The ageing of the population is a global challenge and the period of life spent in good health, although increasing, is not keeping pace with lifespan. Consequently, understanding the important factors that contribute to healthy ageing and validating interventions and influencing policy to promote healthy ageing are vital research priorities. Method: The PANINI project is a collaboration of 20 partners across Europe examining the influence of physical activity and nutrition in ageing. Methods utilised encompass the biological to the social, from genetics to the influence of social context. For example, epigenetic, immunological, and psychological assessments, and nutritional and sports science-based interventions have been used among older adults, as well as mathematical modelling and epidemiology. The projects are multi-disciplinary and examine health outcomes in ageing from a range of perspectives.Results: The results discussed here are those emerging thus far in PANINI from 11 distinct programmes of research within PANINI as well as projects cross-cutting the network. New approaches, and the latest results are discussed.Conclusions: The PANINI project has been addressing the impact of physical activity and nutrition on healthy ageing from diverse but interlinked perspectives. It emphasises the importance of using standardized measures and the advantages of combining data to compare biomarkers and interventions across different settings and typologies of older adults. As the projects conclude, the current results and final data will form part of a shared dataset, which will be made open access for other researchers into ageing processes.
KeyWord	ageing; epigenetics; frailty; genetics; inflammation; nutrition; physical activity; physical function; well-being
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引用本文

Anna C. Whittaker*,Evans A. Asamane,Justin A. Aunger,Dmitriy Bondarev,Andrea Cabbia,Paul D. Doody,Noémie Gensous,Barbara Iadarola,Keenan A. Ramsey,Belina Rodrigues,Muhammad Rizwan Tahir,Suey S.Y. Yeung,on behalf of the PANINI Consortium. Physical Activity and Nutrition INfluences in Ageing: Current Findings from the PANINI Project, Advances in Geriatric Medicine and Research. 2019; 1; (1). https://doi.org/10.20900/agmr20190005.

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