International Journal of Genetics Frontiers

In recent years, relevant research investigations have found that adoptive immunotherapy targeting degenerated antigens can achieve relatively effective results when treating many diseases including tumors, which is also a clinical A new type of treatment with potential and application value. The specificity formed by T cells recognizing antigens is closely related to T cell receptors T cell receptor gene transduction provides a new idea for modern adoptive immunotherapy of tumors, by transferring certain disease-related antigen reactivity T cell clones, T cell receptor genes can make human peripheral blood lymphocytes form corresponding related antigens, and have achieved certain results in clinical treatment of patients, and have provided researchers with new treatment ideas. In this paper, the corresponding research on T cell, receptor gene transduction and application is made, and the technology of T cell gene receptor transduction is analyzed, aiming to provide help and reference for the application of T cell receptor gene transduction technology .

T cell receptor; gene transduction technology; research analysis; immunotherapy