Journal of Advances in Clinical Nursing

Objective Patients with acute myeloid leukemia may have inflammatory reaction in the oral mucosa during chemotherapy. Systematic intervention and nursing can effectively reduce the incidence of oral mucositis. Methods In this experiment, 100 subjects were selected from January 2021 to January 2022. During this period, the selected subjects were adult patients with acute myeloid leukemia who were treated in our hospital. The patients were divided into 1:1 groups, and different nursing methods were implemented to compare the clinical effects of different nursing methods. Results (1) To score the self-care ability, depression and anxiety of patients, there was no significant difference between the two groups before nursing (p>0.05), but after receiving nursing, the two scores of patients in the study group improved more significantly (p<0.05); (2) Compared with the difference of patients treatment compliance, the patients in the study group had higher compliance with nursing measures, the difference was significant (p<0.05). Conclusion during the chemotherapy period of adult acute myeloid leukemia patients, systematic nursing intervention can effectively reduce the probability of inflammatory reaction of patients oral mucosa, improve patients immunity, improve patients psychological status and self-control ability, and make patients more compliant to treatment and nursing measures. It is worth popularizing and applying in clinic.

systematic nursing intervention; Adult acute myeloid leukemia; Chemotherapy; Oral mucositis