复发难治性弥漫大B细胞淋巴瘤患者行嵌合抗原受体T细胞免疫疗法的临床分析
Clinical analysis and nursing observation of patients with relapsed refractory multiple myeloma receivingchimeric antigen receptor T cell immunotherapy
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| DOI |
10.12208/j.jacn.20220238 |
| 刊名 |
Journal of Advances in Clinical Nursing
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| 年，卷(期) |
2022, 1(5) |
| 作者 |
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| 作者单位 |
广西医科大学附属肿瘤医院淋巴血液及儿童肿瘤内科 广西南宁 ;
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| 摘要 |
探讨嵌合抗原受体T细胞（CAR-T）免疫疗法医治复发难治性弥漫大B细胞淋巴瘤弥漫大B细胞淋巴瘤的护理效果。方法 对2020.4~2021.8于我院行CAR-T治疗的35例弥漫大B细胞淋巴瘤患者进行综合护理干预，观察护理情况。结果 仅有1例患者因自行使用其他药物而无法评估疗效，其他34例患者的总有效率达到100.00%，并发症发生率5.88%，均实现了好转出院。结论 弥漫大B细胞淋巴瘤弥漫大B细胞淋巴瘤患者CAR-T进行CAR-T免疫治疗过程中辅助综合护理干预，效果确切，值得推广。
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| Abstract |
Objective To explore the nursing effect of chimeric antigen receptor T cell (car-t) immunotherapy in the treatment of recurrent refractory multiple myeloma. Methods: 35 patients with Diffuse large B-cell lymphoma who were treated with car-t in our hospital from April 2020 to August 2021 were given comprehensive nursing intervention, and the nursing situation was observed. Results: only one patient was unable to evaluate the efficacy due to self use of other drugs. The total effective rate of the other 34 patients reached 100.00%, and the complication rate was 5.88%. All patients were discharged with improvement. Conclusion: the comprehensive nursing intervention assisted by car-t in the process of car-t immunotherapy for Diffuse large B-cell lymphoma patients is effective and worthy of promotion.
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| 关键词 |
复发难治性多发性骨髓瘤；嵌合抗原受体T细胞；免疫疗法；综合护理；效果观察
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| KeyWord |
relapsed refractory multiple myeloma; Chimeric antigen receptor T cells; immunotherapy; Comprehensive nursing; Effect observation
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| 基金项目 |
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| 页码 |
132-134 |
陆凤妮,劳永聪,王石娟,黄思霖,覃丽珍,石夕巧,李灿炎,张丽凤*.
复发难治性弥漫大B细胞淋巴瘤患者行嵌合抗原受体T细胞免疫疗法的临床分析 [J].
临床护理进展.
2022; 1; (5).
132 - 134.