| Abstract |
severe acute pancreatitis is one of the acute abdominal diseases with a high clinical incidence rate. It is caused by the activation of pancreatic enzymes in the pancreas caused by biliary and non biliary causes, which leads to the inflammatory reaction of digestion, edema, bleeding and necrosis of the pancreatic tissue itself, also known as hemorrhagic necrotizing pancreatitis. This disease has the characteristics of acute onset, rapid progress, critical condition and high mortality. Clinically, it is characterized by acute epigastric pain, fever, nausea, vomiting Hematuria amylase elevation and leukocyte count elevation are the main characteristics, which are often complicated by shock, systemic inflammatory response syndrome and multiple organ dysfunction syndrome. At present, there is no effective treatment for severe acute pancreatitis in the clinic. The early view is that the main cause of death of patients with severe acute pancreatitis is pancreatic tissue necrosis, so the medical community continues to try the application of surgery in its treatment process, However, with the deepening of the research, relevant researchers found that the main cause of death of patients with severe acute pancreatitis is not the pancreas itself, but the multiple organ dysfunction and systemic inflammatory reaction caused by pancreatitis. Although the surgical method has a certain therapeutic effect, it is likely to increase the occurrence and spread of infection and increase the occurrence of complications. Therefore, with the deepening of the research on severe acute pancreatitis, The treatment concept is constantly updated. At present, the most commonly used and effective treatment is continuous renal replacement therapy (CRRT). This treatment scheme can steadily remove inflammatory media and poisons from the patients body, supplement a large amount of nutrients for the patient in time, effectively stabilize the patients hemodynamics, and improve the patients quality of life, In this paper, the opportunity and effect of continuous renal replacement therapy for patients with severe acute pancreatitis are described and explained, aiming to provide some basis and reference for clinical treatment.
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