International Journal of Clinical Research

Objective: To analyze the role of chemiluminescence immunoassay in the detection of tumor biomarkers in improving the diagnostic accuracy. Methods: 120 tumor patients treated in our hospital from June 2020 to June 2021 were selected as the observation group; 120 healthy persons who underwent physical examination in our hospital in the same period were selected as the control group. The study subjects were tested for tumor biomarkers by chemiluminescence immunoassay. The tumor conditions were diagnosed by serum carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), carbohydrate antigen 153 (CA153), alpha fetoprotein (AFP) and carbohydrate antigen 125 (CA125), and compared with the results of pathological examination. Results: there were significant differences in CEA, CA199, CA153, AFP and CA125 between the observation group and the control group (P< 0.05). Referring to pathological examination, the diagnostic accuracy of chemiluminescence immunoassay was 97.50% (117 / 120), and the difference was not statistically significant (P> 0.05). Conclusion: using chemiluminescence immunoassay to detect tumor biomarkers can identify five tumor biomarkers, improve the diagnostic accuracy, and has high clinical value.

chemiluminescence immunoassay; Tumor; Biomarker inspection; Diagnostic accuracy