Journal of International Psychiatry

【Abstract】Objective: To explore the influence of clinical outcomes of smoking behavior in the male patients with chronic schizophrenia. Methods: 95 cases of patients with chronic schizophrenia were selected, according to whether patients with smoking, the 95 patients were divided into smoking group (n = 65) and non smoking group (n = 30).Use in hospital nurses observation scale (NOSIE) evaluation of the patients mental condition and daily status, By using positive and negative symptoms scale (positive and negative symptoms scale, PANSS) evaluation of two groups of patients mental symptoms. Results: Smoking NOSIE scale, according to the results of the group of patients with social ability, social interest, always positive factor and total score is significantly higher than control group (P < 0.05), a group of patients with smoking mental factor, slow factor, total negative factor significantly lower than non-smoking patients (P < 0.05), CPT test results show that the group of patients with severe nicotine dependence CPT reflect the number is significantly higher than mild nicotine dependence group and non smoking group (P < 0.05), and patients with mild nicotine dependence group and non smoking group of CPT correct response difference coefficient of no statistical significance (P > 0.05). Smoking group of patients with total scores of PANSS and negative symptoms scale score was significantly lower than non-smoking patients (P < 0.05). Conclusion: Smoking is a kind of behavior can bring a variety of hazards to human health, but there is a risk of cognitive function in patients with chronic schizophrenia and symptoms of schizophrenia may have certain effect.

【Keywords】Smoking; Chronic schizophrenia; Clinical outcomes