Journal of International Psychiatry

Schizophrenia is consider to be a neurodevelopmental disorder and the prodromal phase symptoms are not specific.The clinical identification of ultra-high risk of schizophrenia mainly base on the genetic susceptibility and on the presence and severity of the prodromal syndrome. The neuroimaging study have found abnormal changes of brain structures and functions in the people of ultra-high risk.According to these abnormal changes,clinical diagnosis evalution and mechanism exploration are being discovered.It’s important to doctors to early identify the ultra-high risk groups , reduce the incidence of schizophrenia, improve the prognosis and reduce the burden of disease treatment.

Schizophrenia;ultra high risk ;structural magnetic resonance imaging; functional magnetic resonance imaging