探讨帕金森病合并痴呆患者认知障碍的相关因素

Analysis on the Related Factors of Cognitive Impairment in Patients with Parkinsons disease Dementia and its Impact on the Quality of Life.

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2016, 43(4)
作者
作者单位

南方医科大学珠江医院神经内科 ;
南方医科大学珠江医院 ;

摘要
高筱雅 何雷 郭曦华 覃汉荣【摘要】目的:观察和分析帕金森疾病(PD)合并痴呆患者的认知障碍及其相关影响因素。方法:选取我院2014年6月至2015年10月期间收治的100例帕金森病痴呆患者进行研究,对患者的运动功能、认知功能、智力以及日常生活能力进行评估,并计算认知障碍与其病程、发病年龄、性别、文化程度、运动功能障碍的相关性系数r。结果:100例帕金森病痴呆患者的Webster评分均处于中重度水平,其MoCA评分、MMSE评分以及ADL评分均与正常水平不一致,说明这100例患者均有不同程度的运动功能障碍、认知功能障碍、智力降低以及日常生活能力缺失。认知障碍与病人的病程、发病年龄、性别等因素不相关,与病人的文化程度以及运动功能障碍有紧密关系(P<0.05),差异具有统计学意义。结论:帕金森病痴呆患者的运动能力以及文化程度与病人认知障碍的严重程度关系密切。
Abstract
【Abstract】Objective: To observe and analyze the cognitive impairment in patients with Parkinson disease (PD) dementia and its related influencing factors. Methods: We select from June 2014 to October 2015 admitted during the period of 100 patients with Parkinsons disease dementia, the patients motor function, cognitive function, intelligence and ability of daily life were evaluated and calculate the cognitive impairment and the duration, age of onset, gender, educational level, motor dysfunction the correlation coefficient (r). Results: 100 cases of Parkinsons disease with dementia Webster score were in moderate to severe level and the scores of Moca, MMSE and ADL score were compared to normal levels inconsistent, indicating that reduce the 100 cases of patients had different degrees of motor dysfunction, cognitive impairment, intelligence and daily living ability deficiency. Cognitive impairment with the onset of the patients course of the disease, were not associated with factors such as age, gender, and the patients cultural degree and motion dysfunction has a close relationship (P<0.05), the difference is statistically significant. Conclusion: The patients with Parkinsons disease dementia sports ability and level of education and closely related to the severity of the patients with cognitive impairment.
关键词
【关键词】:帕金森病;痴呆患者;认知障碍
KeyWord
【Key words】: Parkinsons disease; Patients with dementia; Cognitive impairment
基金项目
页码 610-612
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高筱雅,何雷,郭曦华,覃汉荣*. 探讨帕金森病合并痴呆患者认知障碍的相关因素 [J]. 国际精神病学杂志. 2016; 43; (4). 610 - 612.

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