慢性精神分裂症诱导性心血管事件的状况调查及影响因素分析

nalysis of investigation of chronic schizophrenia induced cardiovascular events and influencing factors

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(3)
作者
作者单位

黄冈市黄梅县人民医院 ;

摘要
【摘要】探讨慢性精神分裂症诱导性心血管事件调查情况及影响因素。方法 回顾性分析2013年1月-2016年1月医院138例慢性精神分裂症患者的病例资料,根据有无并发诱导性心血管事件分为心血管事件组(59例)和无心血管事件组(79例),分析两组临床资料的差异,并进行Logostic回归分析。结果 观察组吸烟史、新型抗精神病药物的所占比例高于无心血管事件组(P<0.05);观察组BMI、FPG、FINS、TC、TG、LDL-C、HDL-C高于无心血管事件,载脂蛋白A低于无心血管事件,差异有统计学意义(P<0.05),Logistic回归分析显示,吸烟史、BMI、FPG、TC、HDL-C、抗精神病药物与慢性精神分裂症诱导性心血管事件密切相关。结论 吸烟史、BMI、FPG、TC、抗精神病药物是慢性精神分裂症诱导性心血管事件的独立危险因素,高HDL-C为保护因素。
Abstract
[Abstract] Objective To explore investigation of chronic schizophrenia induced cardiovascular events and influencing factors. Methods A retrospective analysis of clinical data was carried out in 138 patients with chronic schizophrenia from January 2013 to January 2016, they were divided into cardiovascular events group (59 cases) and non cardiovascular events group (79 cases) according to whether they had induced cardiovascular events, differences in clinical data in the two groups were analyzed, Logostic regression analysis was carried out. Results Proportion of smoking history, new type antipsychotic drugs in observation group were higher than non cardiovascular events group (P<0.05); BMI, FPG, FINS, TC, TG, LDL-C, HDL-C in observation group were higher than non cardiovascular events group, apolipoprotein A was significantly lower than non cardiovascular events group (P<0.05); Logistic regression analysis showed that smoking history, BMI, FPG, TC, HDL-C, antipsychotic drugs were closely related to chronic schizophrenia induced cardiovascular events. Conclusion Smoking history, BMI, FPG, TC, antipsychotic drugs are independent risk factors for chronic schizophrenia induced cardiovascular events, high HDL-C is protective factors.
关键词
慢性精神分裂症;心血管事件;抗精神病药物;危险因素
KeyWord
Chronic schizophrenia; Cardiovascular events; Antipsychotic drug; Risk factors
基金项目
页码 433-436
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陈卫公*. 慢性精神分裂症诱导性心血管事件的状况调查及影响因素分析 [J]. 国际精神病学杂志. 2017; 44; (3). 433 - 436.

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