无痉挛电休克及重复经颅磁刺激治疗难治性抑郁症的临床疗效比较-国际精神病学杂志-CSCIED科技核心评价数据库-手机版

无痉挛电休克及重复经颅磁刺激治疗难治性抑郁症的临床疗效比较

The Comparison of Clinical Efficacy between Modified Electroconvulsive Therapy and RepetitiveTranscranial Magnetic Stimulation on the Patients with Treatment Resistant Depression.

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DOI
刊名	国际精神病学杂志 Journal of International Psychiatry
年，卷(期)	2016, 43(2)
作者	郭新宇*,杨　媛,王　琮,田　丽,
作者单位	海南省安宁医院心理康复科 ;
摘要	目的　比较无痉挛电休克（mECT）和重复经颅磁刺激（rTMS）对于改善难治性抑郁症住院患者的临床疗效。方法　选取我院住院治疗的难治性抑郁症患者64例，按照年龄、性别和汉密尔顿抑郁量表（HDRS）评分进行配对，每对患者随机选择进行mECT治疗或rTMS治疗，治疗周期均为4周，治疗后均进行HDRS测量。结果　两组治疗后的HDRS评分均较治疗前有大幅度下降（P <0.05），但是mECT组的减分明显高于rTMS组（t =4.271，P =0.001）；rTMS治疗在改善患者的认知障碍上优于mECT治疗，而mECT治疗在改善迟缓和绝望感方面更为突出。结论　mECT治疗和rTMS治疗均可有效缓解难治性抑郁患者的临床症状，但是mECT的即时疗效明显高于rTMS治疗。
Abstract	【Abstract】 Abstract】Objective To compare the clinical effects of the modified electroconvulsive therapy（mECT）andre- （mECT）andre- mECT）andre- ）andre- and re-petitive transcranial stimulation（rTMS）ontheinpatientswithtreatment resistant depression（TRD）. （rTMS）ontheinpatientswithtreatment resistant depression（TRD）. rTMS）ontheinpatientswithtreatment resistant depression（TRD）. ）ontheinpatientswithtreatment resistant depression（TRD）. on the inpatients with treatment resistant depression（TRD）. （TRD）. TRD）. ）. Methods Therewere 64 inpatients with TRD，whowereequippedwith32pairsbyage，genderandthescoreof HamiltonDepression ，whowereequippedwith32pairsbyage，genderandthescoreof HamiltonDepression who were equipped with 32 pairs by age，genderandthescoreof HamiltonDepression ，genderandthescoreof HamiltonDepression gender and the score of Hamilton DepressionRating Scale（HDRS）. Ineachpair，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo （HDRS）. Ineachpair，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo HDRS）. Ineachpair，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo ）. Ineachpair，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo . In each pair，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo ，thepatientwaschosentobetreatedwithmECTorrTMSbyrandom. Boththetwo the patient was chosen to be treated with mECT or rTMS by random. Both the twotreatments lasted 4 weeks and the HDRS was assessed shortly after the end of the treatments. Results Both the treat-ment by mECT and rTMS declined the score of HDRS（P <0.05），butthemECTwassuperiorontheredcutionofHDRS ），butthemECTwassuperiorontheredcutionofHDRS but the mECT was superior on the redcution of HDRS（t =4.271，P =0.001）；astotheimprovementofcognitivefunction，therTMSwasmorecompetitive，whilethemECT ）；astotheimprovementofcognitivefunction，therTMSwasmorecompetitive，whilethemECT as to the improvement of cognitive function，therTMSwasmorecompetitive，whilethemECT ，therTMSwasmorecompetitive，whilethemECT the rTMS was more competitive，whilethemECT ，whilethemECT while the mECTdid much better on the items of “retardation” and “suicide ideation”. Conclusions Both the treatment of m
关键词	无痉挛电休克治疗；重复经颅磁刺激治疗；难治性抑郁
KeyWord	Modified Electroconvulsive Therapy；RepetitiveTranscranialMagneticStimulation；TreatmentRe- ；RepetitiveTranscranialMagneticStimulation；TreatmentRe- Repetitive Transcranial Magnetic Stimulation；TreatmentRe- ；TreatmentRe- Treatment Re-sistant Depression
基金项目
页码	245-248

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郭新宇*,杨　媛,王　琮,田　丽. 无痉挛电休克及重复经颅磁刺激治疗难治性抑郁症的临床疗效比较 [J]. 国际精神病学杂志. 2016; 43; (2). 245 - 248.

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