Journal of International Psychiatry

【Abstract】Objective To understand the status of treatment of inpatients with schizophrenia in children and adolescents. Methods Survey on the treatment of 258 cases inpatients for the first time with schizophrenia in children and adolescents between January 2010 ~ December 2015. Results Using one atypical antipsychotic drug in 186 cases (72.1%). Two types of antipsychotic drugs in combination were 72 cases（27.9%）. Using Risperdal first in 66 cases（25.6%），Olanzapine second in 56 cases（21.7%）and Aripiprazole third in 35 cases（13.6%）. Men use Risperdal more than women and women use Aripiprazole more than men at discharge. The statisticaldifferences were significantly(x2=9.905,8.380，P<0.01). Combination using with antidepressants in 48 cases（18.6%），mood stabilizers in 16 cases（6.2%）and BDZ in 32 cases（12.4%）at discharge. There were no significantly statistical differences in comparison of different gender and age（x2=0.016~1.482，P>0.05）. Conclusion Drug treatment in patients with schizophrenia in children and adolescents was basically reasonable. Drug treatment was main single using atypical antipsychotics. Gender differences of using risperidone and aripiprazole which associated with pharmacology and its side effects. A few patients combined combined two antipsychotic drugs, antidepressants and mood stabilizers which associated with illness. BZD should be used cautiously.

【Keywords】Schizophrenia；Children and adolescents ；Treatment ；Cross-sectional investigation