探讨影响首次发病的老年精神分裂症患者预后因素的Logitic回归分析

Factors ofaffecting the prognosis of patients with senile schizophrenia Logitic regression analysis

ES评分 0

DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(3)
作者
作者单位

湖北省宜昌市精神卫生中心 ;
湖北省人民医院 ;

摘要
【摘要】探讨影响首次发病的老年精神分裂症患者(年龄≥60岁)预后因素的Logitic回归分析。方法 收集2013年2月至2015年2月在我院住院的首次发病的老年精神分裂症患者256例为研究对象,按照出院后随访1年时的大体评定量表(GAS)评分将患者分为A组(预后不良组,GAS<61分, n=71例)和B组(预后良好组,GAS≥61分, n=185例),比较两组一般临床资料、实验室检查指标的差异,并利用Logistic回归方程分析影响老年精神分裂症患者预后因素的相关因素。 结果 单因素分析提示两组患者在受教育程度、婚姻状况、家庭经济收入、高血压、代谢综合症、血清超敏C反应蛋白(hs-CRP)、D-二聚体、泌乳素方面存在统计学差异(P<0.05);多因素Logistic回归分析最终筛选出家庭经济收入偏低、合并高血压、代谢综合症、血清hs-CRP≥7 mg/L、D-二聚体≥400μg/L、泌乳素≥30μg/L是老年精神分裂症患者(年龄≥60岁)预后不良的独立危险因素。 结论 首次发病的老年精神分裂症患者预后情况受到诸多因素影响,庭经济收入偏低、合并高血压、代谢综合症、高水平血清hs-CRP、D-二聚体、泌乳素等是其独立影响因素,应当引起临床中高度重视。
Abstract
【 abstract 】 objective to investigate the influence of elderly patients with schizophrenia (age 60 or higher) Logitic regression analysis of prognostic factors. Method selection in February 2014 to May 2016 in our hospital 256 cases of senile schizophrenia patients in the hospital as the research object, according to the follow-up of 1 year after discharge gross rating scale (GAS) score divided the patients into group A (poor prognosis group, GAS < 61 points, n = 71) and group B (good prognosis group, GAS 61 points or more, n = 185), compared two groups of general clinical data, laboratory examination indexes, and by using Logistic regression equation analysis of the factors affecting the prognosis of patients with senile schizophrenia related factors. Results single-factor analysis two groups of patients in the level of education, marital status, family income, hypertension, metabolic syndrome and serum hypersensitive c-reactive protein (hs - CRP), D - dimer, prolactin statistical differences (P < 0.05); Multiariable Logistic regression analysis of finally selected family economic income is low, hypertension, metabolic syndrome, hs - CRP serum p 7 mg/L, D - dimer acuity 400 mu g/L, prolactin acuity 30 mu g/L is elderly schizophrenia patients (age 60 or higher) independent risk factors of poor prognosis. Conclusion the prognosis of patients with senile schizophrenia is affected by many factors,Family economic income is low, hypertension, metabolic syndrome, high levels of serum hs - CRP, D - dimer and prolactin were independent factors affecting its, should cause attaches great importance in the clinical.
关键词
【关键词】精神分裂症;老年人;Logitic回归方程;危险因素;
KeyWord
【 key words 】 schizophrenia; The elderly; Logitic regression equation; Risk factors
基金项目
页码 406-410
  • 参考文献
  • 相关文献
  • 引用本文

姚雪阳*,汤世明,蔡枫,常程. 探讨影响首次发病的老年精神分裂症患者预后因素的Logitic回归分析 [J]. 国际精神病学杂志. 2017; 44; (3). 406 - 410.

  • 文献评论

相关学者

相关机构