右美托咪定联合瑞芬太尼与咪达唑仑联合芬太尼在ICU谵妄发生率的比较

Comparison of the incidence of delirium in ICU with dexmetomidine combined with remifentanil and midazolam combined with fentanyl

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2019, 46(2)
作者
作者单位

湖南省湘阴县人民医院 ;

摘要
【摘要】 目的: 比较重症医学科(ICU)患者采用右美托咪定联合瑞芬太尼与咪达唑仑联合芬太尼所致谵妄的发生率。方法: 选取2015年6 月至 2017年10月我科收治的78例患者,按照随机数字表法分为右美托咪定联合瑞芬太尼组(YRF组)和咪达唑仑联合芬太尼组(MF组)各39例,分别给予右美托咪定联合瑞芬太尼与咪达唑仑联合芬太尼镇静镇痛。比较两组谵妄的发生率。结果: 两组镇静镇痛评分差异无统计学意义(p>0.05)。镇静镇痛过程中,右美托咪定联合瑞芬太尼组谵妄发生率低于咪达唑仑联合芬太尼组(p<0.05)。结论: ICU谵妄是一组常见的重症监护病房临床综合征,使用右美托咪定联合瑞芬太尼镇静镇痛谵妄发生率较低。
Abstract
【abstract】 objective:To compare the incidence of delirium induced by dexmetomidine combined with rifentanil and midazolam combined with fentanyl in ICU patients. Methods: Select in June 2015 to October 2017 of 78 patients admitted in our department, according to the random number table method is divided into the right mi fixed joint, fentanyl group (YRF) and midazolam fentanyl group (MF), 39 cases were given the right holder mi fixed joint, fentanyl and midazolam combined fentanyl sedation analgesia. The incidence of delirium in the two groups was compared. Results: There was no significant difference in sedation and analgesia scores between the two groups (p>0.05). In the course of sedation and analgesia, the incidence of delirium in dexmedetomidine combined with remifentanil group was lower than that in midazolam plus fentanyl group (p<0.05). Conclusion: ICU delirium is a common clinical syndrome in ICU. The incidence of delirium is low when using dexmedetomidine combined with remifentanil for sedation and analgesia.
关键词
【关键词】右美托咪定;瑞芬太尼;咪达唑仑;芬太尼;ICU;镇静镇痛;谵妄
KeyWord
【key words】 Dexmetomidine; Remifentanil; Midazolam; Fentanyl; ICU; Sedative analgesia; Delirium.
基金项目
页码 312-315
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陈卓荦*. 右美托咪定联合瑞芬太尼与咪达唑仑联合芬太尼在ICU谵妄发生率的比较 [J]. 国际精神病学杂志. 2019; 46; (2). 312 - 315.

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