经颅多普勒超声下血流动力学与血管性认知功能障碍患者认知功能的相关性

Correlation between hemodynamics under transcranial Doppler ultrasound and cognitive function in patients with vascular cognitive impairment

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2021, 48(3)
作者
作者单位

开封市人民医院超声科 ;

摘要
【摘要】 分析血管性认知功能障碍患者认知功能与经颅多普勒超声下血流动力学水平的相关性。方法 选取我院52例血管性认知障碍患者进行研究,选取同时间段在我院治疗的51例血管性疾病但未合并认知障碍患者作为常规组,52例血管性认知障碍患者作为实验组,采用经颅多普勒超声及蒙特利尔认知评估量表(MoCA)检查患者大脑前动脉搏动指数(ACA-PI)、大脑中动脉搏动指数(MCA-PI)、大脑前动脉平均血流速度(ACA-Vm)、大脑中动脉平均血流速度(MCA-Vm),并评估患者认知功能,明确脑动脉搏动指数、血流速度与认知功能的相关性。结果 实验组ACA-PI、MCA-PI水平高于常规组,视空间/执行功能、注意力、命名、定向力、记忆、抽象能力、语言及MoCA总分均低于常规组(P<0.05);多元线性回归分析显示MCA-PI与MoCA评分呈负相关(P<0.05)。结论 经颅多普勒超声检查显示,血管性认知障碍患者大脑前动脉、中动脉阻力均显著提升,大脑中动脉搏动指数与患者认知功能呈负相关。
Abstract
[Abstract] Objective To analyze the correlation between cognitive function and hemodynamic level under transcranial Doppler ultrasound in patients with vascular cognitive impairment. Methods Fifty-two patients with vascular cognitive impairment in our hospital were selected for the study, 51 patients with vascular disease but without cognitive impairment who were treated in our hospital at the same time period were selected as the routine group, and 52 patients with vascular cognitive impairment were selected as the experiment group,Transcranial Doppler ultrasound and Montreal Cognitive Assessment Scale (MoCA) were used to check the anterior cerebral artery pulsatility index (ACA-PI), middle cerebral artery pulsatility index (MCA-PI), and average blood flow velocity of the anterior cerebral artery (ACA). -Vm), the mean blood flow velocity of the middle cerebral artery (MCA-Vm), and evaluate the cognitive function of the patient, and clarify the correlation between the cerebral artery pulsation index, blood flow velocity and cognitive function. Results The levels of ACA-PI and MCA-PI of the experimental group were higher than those of the conventional group, and the total scores of visual space/executive function, attention, naming, orientation, memory, abstract ability, language and MoCA were lower than those of the conventional group (P<0.05) ; Multiple linear regression analysis showed that MCA-PI was negatively correlated with MoCA score (P<0.05). Conclusion Transcranial Doppler ultrasonography showed that the resistance of the anterior cerebral artery and the middle artery in patients with vascular cognitive impairment increased significantly, and the pulsation index of the middle cerebral artery was negatively correlated with the cognitive function of the patients.
关键词
【关键词】经颅多普勒超声;血流动力学;血管性认知功能障碍;认知功能
KeyWord
[Keywords] transcranial Doppler ultrasound; hemodynamics; vascular cognitive dysfunction; cognitive function
基金项目
页码 500-502
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王宇*. 经颅多普勒超声下血流动力学与血管性认知功能障碍患者认知功能的相关性 [J]. 国际精神病学杂志. 2021; 48; (3). 500 - 502.

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