帕罗西汀对冠心病合并失眠患者睡眠质量及不良心理状态的影响
Effect of paroxetine on sleep quality and adverse mental state in patients with coronary heart disease complicated with insomnia
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年,卷(期) |
2022, 49(4) |
| 作者 |
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| 作者单位 |
河南科技大学附属许昌市中心医院心血管一病区 ;
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| 摘要 |
【摘要】探究帕罗西汀应用于冠心病合并失眠患者疗效及对抑郁、焦虑情绪的影响。方法 选取我院113例冠心病(CHD)伴失眠患者以随机数字表法分组。对照组56例给予分级心理干预,观察组57例在此基础上增加帕罗西汀药物治疗,对比两组患者临床疗效;焦虑抑郁情绪:汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD);睡眠质量:匹兹堡睡眠质量指数(PSQI)各项评分。结果:治疗后观察组HAMA、HAMD、PSQI各项评分及总分均低于对照组,总有效率高于对照组(P<0.05)。 结论:帕罗西汀联合分级心理干预对冠心病合并失眠患者治疗,可有效提高睡眠质量,降低焦虑抑郁情绪,提升临床疗效。
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| Abstract |
【 Abstract 】 Objective To explore the efficacy of paroxetine in patients with coronary heart disease complicated with insomnia and its effect on depression and anxiety. Methods 113 patients with coronary heart disease (CHD) with insomnia in our hospital were divided into groups by random number table method. The control group (n=56) was given graded psychological intervention, and the observation group (n=57) was given paroxetine drug treatment on this basis, and the clinical efficacy of the two groups was compared. Anxiety and depression: Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD); Sleep quality: Pittsburgh Sleep Quality Index (PSQI) scores. Results: After treatment, the scores and total scores of HAMA, HAMD and PSQI in the observation group were lower than those in the control group, and the total effective rate was higher than that in the control group (P<0.05). Conclusions: Paroxetine combined with graded psychological intervention can effectively improve sleep quality, reduce anxiety and depression, and enhance clinical efficacy in patients with coronary heart disease complicated with insomnia.
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| 关键词 |
【关键词】帕罗西汀;冠心病;失眠;焦虑抑郁
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| KeyWord |
【 Key words 】 Paroxetine; Coronary heart disease (CHD). Insomnia; Anxiety depression
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| 基金项目 |
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| 页码 |
662-664 |
王喜红*.
帕罗西汀对冠心病合并失眠患者睡眠质量及不良心理状态的影响 [J].
国际精神病学杂志.
2022; 49; (4).
662 - 664.