International Research in Chinese Medicine

Objective To study the characteristics of TCM syndrome differentiation of psoriasis vulgaris between Uyghur and Han nationalities and their similarities and differences with their correlation with T cell subsets, so as to provide a basis for the development of differentiated treatments in the next step. Methods The epidemiological investigation method was used to make an observation table, and the main and concurrent syndromes of the two groups of patients were counted. At the same time, flow cytometry was used to measure the number of CD3, CD4, and CD8 T lymphocytes, and the ratio of CD4/CD8 was calculated. , and compared and analyzed the syndrome differentiation results and experimental data of the two groups of patients, and summarized the similarities and differences. Results The blood dryness syndrome, dampness type, and spleen deficiency type in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in T cell subsets CD3, CD4, CD8 and CD4/CD8 between the two groups (P>0.05). Conclusion The TCM syndrome differentiation of psoriasis vulgaris in Uyghur and Han nationalities is mainly based on blood heat syndrome, but blood dryness syndrome, dampness type, and spleen deficiency type are more common in Uyghur patients than in mainland Han patients, and attention should be paid when treating and using drugs.

Uygur; Han; Psoriasis; Syndrome differentiation; T cell subsets