| Abstract |
Objective To explore and retrospectively analyze the observation and nursing points of continuous renal replacement therapy (CRRT) in the treatment of severe acute renal failure (ARF). Methods 90 patients with ARF who underwent CRRT in our hospital from August 2020 to September 2021 were randomly divided into reference group (intermittent hemodialysis treatment) and study group (ARF treatment), with 45 cases in each group. The levels of inflammatory factors such as interleukin-6 (IL-6), interleukin-8 (IL-8), high-sensitivity C-reactive protein (hs CRP), tumor necrosis factor-A (TNF-a), renal function indexes such as serum creatinine (SCR), endogenous creatinine clearance (CCR), urea nitrogen (BUN), cholinesterase (CHE), treatment effect and complications were compared between the two groups, and the key points of nursing were summarized. Results the effective rate of the study group was 95.56% higher than 77.78% in the reference group (P < 0.05); Study group IL-6, IL-8, hs CRP, TNF- α All were lower than those in the reference group (P < 0.05); The levels of SCR, CCR, bun and ChE in the study group were better than those in the reference group (P < 0.05); The incidence of complications in the study group was 4.44%, which was lower than 22.22% in the reference group (P < 0.05). Conclusion CRRT can reduce the level of inflammatory factors and the incidence of complications, improve renal function and improve the therapeutic effect.
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