International Journal of Clinical Research

Objective: To analyze the effect of fluconazole combined with corneal debridement on the recovery of vision and corneal symptoms in patients with fungal keratitis. Methods: A total of 60 patients with fungal keratitis who were treated from May 2020 to May 2022 were selected and grouped by random number table method, that is, 30 cases in the control group were treated with corneal debridement, and 30 cases in the observation group were treated with flucon azole combined with corneal debridement, and the effect of the two groups was compared. Results: Compared with the control group, the observation group had a higher effective rate, P<0.05; compared with the control group, the observation group had shorter corneal healing time, smaller ulcer area, fewer operations, and better visual acuity recovery, P<0.05; compared with the control group, the observation group The incidence of complications in the group was lower, P<0.05. Conclusion: Fluconazole combined with corneal debridement has a significant effect in the treatment of fungal keratitis, which can not only improve the corneal symptoms of patients, promote the recovery of vision, but also reduce complications and improve the effective rate.

Fungal Keratitis; Fluconazole; Corneal Debridement; Visual Acuity; Corneal Symptom Recovery