International Journal of Internal Medicine

Objective Clopidogrel and aspirin combined therapy were performed in patients with acute cerebral infarction, and to analyze the actual effect after application. Methods 64 patients with acute cerebral infarction were treated from June 2021 to May 2022 patients, and were divided into two groups. The control group was single aspirin, and clopidogrel and aspirin in the observation group. Results According to the data, the observation group had better disease control effect, with lower inflammatory factors (tumor necrosis factor, high-sensitive C-33) than the control group, which was statistically significant (P <0.05). Meanwhile, in the coagulation function index APTT and PT comparison, the observation group maintained the advantage, and the data was higher than the control, with a significant difference (P <0.05). Finally, in the quality of life measurement QOL scale results, the patients in the observation group also had higher index results than the control group, with significant differences (P <0.05). Conclusion Clopidogrel and combined aspirin were effective for patients with acute cerebral infarction, which quickly alleviated the clinical symptoms and improved the inflammatory response and blood coagulation function index.

Clopidogrel; Aspirin; Acute cerebral infarction; Quality of life; Inflammatory factors; Coagula- tion function