International Journal of Clinical Research

Objective: To analyze the application value of narrow-band imaging and iodine staining in early esophageal cancer screening. Methods: The clinical data of 1089 outpatients and inpatients who underwent routine gastroscopy in our hospital from August 2020 to December 2021 were retrospectively analyzed. All patients underwent narrow-band imaging (NBI) and iodine staining before pathological examination. According to the screening method, the patients were divided into control group (narrowband imaging technique) and experimental group (narrowband imaging technique combined with iodine staining). The diagnostic value of the two screening methods was compared with pathological examination as the gold standard. Results: Among 1089 patients undergoing routine gastroscopy, 142 (13.04%) cases of pure NBI biopsy in the control group, including 3 cases of cervical segment, 37 cases of upper thoracic segment, 67 cases of middle thoracic segment, and 35 cases of lower thoracic segment. In the experimental group, the number of biopsies by narrow-band imaging combined with iodine staining was 180 (16.53%), including 3 cases of cervical lesions, 42 cases of upper thoracic lesions, 83 cases of middle thoracic lesions, and 52 cases of lower thoracic lesions. Detection, 12 cases of early esophageal cancer cases in control group, found that the low level of lesion number 16 cases, 10 cases of high level lesion, 2 cases were carcinoma in situ, detection of early esophageal cancer cases in the observation group and control group in the same, but found that low level number of lesions (20), high level of lesion (14), carcinoma in situ (2 parts). There was no significant difference in the number of cases detected between the two groups (P > 0.05), but although the number of early esophageal cancer cases did not increase after combined iodine staining, multiple lesions were found in the same patient. Conclusion: Both narrow-band imaging and iodine staining have ideal screening and diagnostic value in early esophageal cancer screening, but the combination of them can further improve the diagnostic effect.

Early Esophageal Cancer; Narrow Band Imaging; Iodine Staining; Joint Inspection; Application Value