International Journal of Clinical Research

Objective To compare the effect of amiodarone and proparadenone treatment in prehospital emergency treatment in patients with rapid arrhythmia. Methods The patients admitted in the emergency department were 100 patients from January 2020 to December 2021. The group was randomly ized by computer into amine iodine group (n=50) and Proa group (n=50). The amine iodinated group was treated with amiodarone and the propa group was treated with propadone. The treatment effect, the incidence of adverse drug reactions, and the index level of HRV parameters before and after treatment were compared between the two groups. Results The response rate of treatment was 98.00%, higher than that of Proa group (P <0.05). Adverse reactions in amine iodine group were 4.00%, which was lower than that in proa group (P <0.05). The levels of sDNNindex, SDNN and rMSSD were higher in the amine-iodine group than in the proa group (P <0.05). Conclusion Amiodarone is better than properazenone, and the drug safety is recommended.

Amiodarone; Properazone; Rapid Arrhythmia; Pre-Hospital First Aid; Treatment Effect