| Abstract |
Objective To analyze the clinical effect of different blood purification modes in the treatment of patients with end-stage renal disease. Methods 96 patients with end-stage renal disease in our hospital from January 2020 to December 2021 were divided into two groups by double-blind random method. The control group was given conventional hemodialysis, and the experimental group was given high-flux hemodialysis. The levels of parathyroid hormone, blood phosphorus, blood urea nitrogen, blood creatinine, β-2 microglobulin, inflammatory stress level, infection, imbalance syndrome, skin itching and other complications were compared between the two groups before and after treatment. Results The levels of parathyroid hormone, blood phosphorus, blood urea nitrogen, serum creatinine, β-2 microglobulin, and inflammatory stress levels were compared between the two groups before treatment, P>0.05. The levels of serum phosphorus, blood urea nitrogen, serum creatinine, β-2 microglobulin, and inflammatory stress were significantly decreased, while the levels of parathyroid hormone, blood phosphate, β-2 microglobulin, and inflammatory stress in the experimental group were significantly reduced. The stimulation level was significantly lower than that of the control group, P<0.05. The blood urea nitrogen and serum creatinine levels were not significantly different from the control group, P>0.05. Conclusion The effect of high flux hemodialysis in patients with end-stage renal disease is accurate, which can further improve dialysis adequacy, better clear β-2 microglobulin and parathyroid hormone, and can better control the level of inflammatory stress in the body and reduce complications disease occurs.
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