Journal of International Psychiatry

【Abstract】 Objective: To investigate the effects of mirtazapine and domperidone combined treatment effect on hypertension and proteinuria in patients with depression and anxiety. Methods: from January 2014 to January 2016 in our hospital for treatment of hypertensive patients with depression and anxiety in patients with a total of 180 cases patients according to the admission number, were randomly divided into three groups, A, B, C three groups of 60 patients, A group were treated with Mi Danping therapy; B group were treated with domperidone treatment; group C patients the combined treatment method for patients receiving 2 weeks of treatment, the urinary protein of two groups of patients to improve the situation. Results: C group of patients with urinary protein content significantly decreased, blood pressure can be controlled effectively; and the patients in the C group received combined treatment, the total number of the occurrence of adverse reactions in 5 cases, and the number of A group and B group were 42 cases and 57 cases, the occurrence of adverse reactions was significantly higher than C group. Between group treatment effects compared with the difference, P < 0.05. Conclusion: in the clinical treatment of hypertension patients with depression and anxiety disorders, can use mirtazapine and domperidone combined treatment method, can effectively improve the urinary protein content, improve the quality of life of patients, obtain the ideal treatment effect, it is worthy of clinical promotion.

【Keywords】: Hypertension anxiety and depression comorbidity; Mi Danping; Pan Litong; urinary protein