International Research in Chinese Medicine

Objective To explore the clinical efficacy and safety of Professor Lai Xiangquan's modified Shaoyao Decoction in treating intestinal hemorrhoids with damp-heat accumulation and qi stagnation with blood stasis. Methods The study subjects were 306 patients with intestinal hemorrhoids due to damp-heat accumulation and qi stagnation with blood stasis (from November 2023 to July 2025). All patients were treated with Professor Lai's modified Shaoyao Decoction for a 4-week course. Results After 4 weeks of treatment, the total scores of clinical symptoms and individual symptom scores in both groups decreased compared to before treatment, and abnormal tongue and pulse manifestations improved to varying degrees. The comparison between the groups showed that the observation group had lower scores for individual symptoms and total scores, and a higher total improvement rate of tongue and pulse (P < 0.05). The efficacy evaluation indicated that the total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). Conclusion Professor Lai Xiangquan's modified Shaoyao Decoction is effective in treating intestinal hemorrhoids with damp-heat accumulation and qi stagnation with blood stasis, significantly improving the clinical symptoms of patients, and has high safety. The modified formula is well-structured and fully embodies the characteristics of TCM syndrome differentiation and treatment.

Modified shaoyao decoction; Damp-heat accumulation; Qi stagnation with blood stasis; Intestinal hemorrhoids; Clinical experience