International Journal of Clinical Research

Objective To explore the influencing factors of adverse cardiovascular events (MACE) in elderly (≥ 75 years old) patients with coronary heart disease after percutaneous coronary intervention (PCI). Methods 100 elderly patients with coronary heart disease who underwent PCI in our hospital from January 2023 to January 2025 were selected as the study subjects. They were divided into an event group (with MACE occurrence, n=28) and a non event group (without MACE occurrence, n=72) based on whether MACE occurred within 6 months after surgery. Collect patient baseline data, surgical related indicators, and postoperative management indicators, use univariate analysis to screen for differential variables, and use multivariate logistic regression analysis to determine independent influencing factors for MACE occurrence. Results Univariate analysis showed that the history of diabetes, multi vessel disease, left ventricular ejection fraction (LVEF)<50%, postoperative antiplatelet drug non-compliance, and postoperative low-density lipoprotein cholesterol (LDL-C) ≥ 1.8 mmol/L in the event group were higher than those in the non event group (P<0.05); Multifactor logistic regression analysis showed that the history of diabetes, multi vessel disease LVEF<50%、 Postoperative non-compliance with antiplatelet drugs and postoperative LDL-C ≥ 1.8mmol/L are independent risk factors for MACE in elderly patients with coronary heart disease after PCI (P<0.05). Conclusion The occurrence of MACE after PCI in elderly patients with coronary heart disease is closely related to the history of diabetes, multi vessel disease, cardiac dysfunction (LVEF<50%), postoperative antiplatelet non-compliance and poor blood lipid control. It is necessary to develop individualized intervention programs for these risk factors to reduce the risk of adverse events after surgery.

Elderly coronary heart disease; Percutaneous coronary intervention therapy; Adverse cardiovascular events