International Journal of Clinical Research

Objective To analyze the role of information closed-loop management in promoting the safe use of neonatal parenteral nutrition preparations. Methods A retrospective analysis was conducted on 2883 prescriptions of parenteral nutrition solution in the Pharmacy Department of Yiwu Maternal and Child Health Hospital from January 2023 to October 2023, which were set as the control group before the implementation of information closed-loop management; From January 2024 to October 2024, the prescription status of 3402 parenteral nutrition solutions in the intravenous drug dispensing center was set as the observation group after the implementation of information closed-loop management. Compare the usage of parenteral nutrition preparations before and after the implementation of the information closed-loop management mode. Results (1) The error rate of the observation group was significantly lower than that of the control group (P<0.05), indicating a statistically significant difference. (2) There are errors in the issuance of medical orders, prescription review, medication dispensing, drug preparation, product verification, packaging and transportation, and discrepancies between wristbands and drug information in the process of using neonatal parenteral nutrition preparations. The observation group had significantly lower errors in prescription issuance, prescription review, medication dispensing, drug preparation, finished product verification, and packaging and transportation compared to the control group (P<0.05), indicating a statistically significant difference. Conclusion Information closed-loop management reduces the incidence of errors in the use process of parenteral nutrition preparations, ensuring medication safety and effectiveness.

Information closed-loop management; Newborn; Parenteral nutrition preparations; Prescription; Error event