International Journal of Clinical Research

Objective To explore the efficacy of levofloxacin combined with tinidazole in the acute attack stage of chronic pelvic inflammatory disease and its influence on the levels of inflammatory factors. Methods From June 2022 to May 2025, 100 patients with acute exacerbation of chronic pelvic inflammatory disease were selected as the research subjects. The patients were divided into two groups by digital random table method. The control group was treated with tinidazole monotherapy, while the observation group was treated with levofloxacin in combination on this basis. The therapeutic effects were compared. Results The therapeutic effect of the observation group was more significant than that of the control group, and the comparison was statistically significant (P < 0.05). The levels of inflammatory factors in the observation group decreased more significantly than those in the control group, and the comparison was statistically significant (P < 0.05). Conclusion During the acute attack period of chronic pelvic inflammatory disease, the treatment with levofloxacin combined with tinidazole not only has a relatively significant therapeutic effect, but also helps patients reduce the levels of inflammatory factors.

Levofloxacin; Tinidazole; Chronic pelvic inflammatory disease; Acute attack period; Levels of inflammatory factors