International Journal of Clinical Research

Objective To observe the effect of noxious stimulation index (NOx) in guiding the use of general anesthesia in elderly patients undergoing thoracoscopic lobectomy. Methods from October 2023 to March 2024, 66 elderly patients over 65 years old undergoing thoracoscopic lobectomy in Qingyuan Hospital Affiliated to Guangzhou Medical University were selected as the research samples, and were divided into two groups according to whether the patients carried out NOx monitoring during the operation, namely, the experimental group NOx group and the control group BIS group. The SSI value in the NOx group was maintained between 40-60, the NOx value was maintained between 40-60, and the BIS value in the BIS group was maintained between 40-60. The dosage of anesthetics and perioperative neurocognitive impairment in the two groups were analyzed. Results the dosage of anesthetic drugs in NOx group and patients during operation was lower than that in BIS group, P<0.05. The incidence of perioperative neurocognitive impairment in NOx group was lower than that in BIS group, P<0.05. Conclusion in the process of thoracoscopic lobectomy in the elderly, noxious stimulation index (NOx) is used to guide the use of general anesthesia, which is helpful to reduce the use of narcotic drugs, reduce the incidence of perioperative neurocognitive impairment, and help patients recover.

Noxious stimulation index (NOx); Laparoscopic lobectomy; Neurocognitive impairment