International Journal of Clinical Research

Objective To investigate the effects of Jiuxin Pill combined with routine treatment on glucose and lipid metabolism and cardiac function in elderly patients with type 2 diabetes mellitus and coronary artery disease, and to evaluate its clinical application value. Methods 124 elderly patients with type 2 diabetes mellitus and coronary artery disease treated in our hospital from January 10, 2023 to January 10, 2024 were selected and randomly divided into a control group (n=62) and an observation group (n=62). The control group received routine hypoglycemic, lipid-lowering, and anti-anginal treatment, while the observation group received Jiuxin Pill in addition to routine treatment, one pill twice daily for 8 weeks. Fasting plasma glucose (FPG), glycated hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TG), left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD), and brain natriuretic peptide (BNP) levels were observed before and after treatment in both groups. SPSS 26.0 software was used for statistical analysis. Results After treatment, the levels of FPG, HbA1c, TC, and TG in the observation group were significantly lower than those in the control group (P < 0.05), LVEF was significantly higher (P < 0.01), and LVEDD and BNP levels were significantly lower (P < 0.05). Simultaneously, HAMA and HAMD scores were significantly reduced (P < 0.05), indicating effective relief of anxiety and depression in patients. Conclusion The combination of Jiuxin Pill and conventional treatment can effectively improve glucose and lipid metabolism disorders and cardiac function in elderly patients with type 2 diabetes and coronary heart disease, and can also significantly alleviate anxiety and depression, demonstrating more comprehensive clinical intervention value.

Jiuxin Pill; Type 2 diabetes; Coronary heart disease; Glucose and lipid metabolism