International Journal of Clinical Research

Objective To explore the application effect of remimazolam combined with remifentanil anesthesia in painless gastroscopy and colonoscopy for elderly patients. Methods The study period was from June 2024 to June 2025. There were 100 patients, they were evenly divided into a control group and an experimental group, with 50 cases in each group. The control group consisted of propofol combined with remifentanil. Experimental group: Remimazolam combined with remifentanil. The anesthesia indicators, hemodynamic parameters, and cognitive function were compared between the two groups.. Results The anesthesia indicators of the patients in the experimental group were better than those in the control group, p<0.05. The hemodynamic indicators of the experimental group were better than those of the control group, p<0.05. The cognitive function of the experimental group was better, p<0.05. Conclusion The use of remimazolam combined with remifentanil for anesthesia during painless gastroscopy and colonoscopy in elderly patients can improve the anesthesia status of patients, stabilize hemodynamic indicators, and reduce the impact on patients' cognitive function.

Remimazolam; Remifentanil anesthesia; Elderly patients; Painless gastroscopy and colonoscopy; Application effect