International Journal of Clinical Research

Objective To explore the application value of peripheral blood smear morphology combined with automatic hematology analyzer in the detection of iron deficiency anemia. Methods A total of 100 patients participated in this study from March 2024 to March 2025. All patients underwent detection using an automatic hematology analyzer, peripheral blood smear morphology examination, and bone marrow iron staining. Patients were divided into a control group and an experimental group according to whether they had anemia: the control group without anemia and the experimental group with anemia, with 50 cases in each group. Routine blood indicators, cellular morphological characteristics, and diagnostic efficacy were compared between the two groups. Results RBC, Hb, MCV, MCH, and MCHC levels in the experimental group were lower than those in the control group (p<0.05), while RDW levels were higher (p<0.05). Differences were observed in cellular morphological characteristics between the two groups (p<0.05). Analysis of diagnostic efficacy showed that combined diagnosis had higher accuracy (p<0.05). Conclusion Using peripheral blood smear morphology combined with automatic hematology analyzer for patients with iron deficiency anemia can improve diagnostic efficacy and has good economic value.

Peripheral blood smear morphology; Automated hematology analyzer; Iron deficiency anemia; Diagnosis