肺癌术后患者并发静脉血栓栓塞危险因素分析-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

肺癌术后患者并发静脉血栓栓塞危险因素分析

Analysis of risk factors of postoperative venous thromboembolism in lung cancer patients

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DOI	10.12208/j.ijcr.20260121
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2026, 10(3)
作者	崔晓海², 党国信¹, 孙彤宇¹,
作者单位	兵器工业卫生研究所肝胆与血管外科陕西西安; 西安交通大学第一附属医院胸外科陕西西安;
摘要	目的探讨肺癌术后并发静脉血栓栓塞的高危因素。方法收集2024年8月-2025年8月在西安交通大学第一附属医院胸外科接受肺癌手术治疗的150例患者的临床资料。根据术后有无并发静脉血栓栓塞将所有患者分为静脉血栓栓塞组30例和无静脉血栓栓塞组120例。回顾性分析患者的临床资料，比较两组患者在一般资料、术前辅助检查结果、手术相关因素、术后病理相关因素等方面的差异。采用多因素logistic回归分析肺癌术后并发静脉血栓栓塞的危险因素。结果两组患者在年龄、术前CEA水平、D-二聚体、白细胞、红细胞、肺功能水平、手术方式、手术范围、手术时间、术中出血量等方面差异有统计学意义（P＜0.05）；多因素Logistic回归分析结果显示，术前D-二聚体水平、红细胞水平、FEV1水平、手术方式、手术时间是肺癌术后患者并发静脉血栓栓塞的独立危险因素（P＜0.05）。结论术前D-二聚体水平升高、红细胞水平降低、FEV1水平降低、开胸手术、手术时间较长的肺癌患者手术后易发生静脉血栓栓塞。
Abstract	Objective To explore the risk factors of postoperative venous thromboembolism in lung cancer patients. Methods The clinical data of 120 lung cancer patients who underwent surgery in our hospital from August 2024 to August 2025 were collected. 150 lung cancer patients who underwent surgery were divided into venous thromboembolism group (n=30) and non-venous thromboembolism group (n=120) according to whether venous thromboembolism occurred after operation. The clinical data of the patients were retrospectively analyzed. And the differences between the two groups in general data, preoperative auxiliary examination results, operative related factors and postoperative pathological related factors were compared. Multivariate logistic regression was used to analyze the risk factors of postoperative venous thromboembolism of the two groups of patients. Results There were significant differences in age, preoperative CEA levels, preoperative D-dimer levels, white blood cell count, red blood cell count, lung function levels, surgical procedures, surgical scope, operation time and blood loss between the two groups (P＜0.05). Logistic regression analysis showed that preoperative D-dimer levels, red blood cell count, forced expiratory volume in one second (FEV1), surgical procedures and operation time were independent risk factors for postoperative venous thromboembolism in lung cancer patients. Conclusions The lung cancer patients who were with higher levels of preoperative D-dimer, lower red blood cell count, lower levels of FEV1, open thoracotomy and longer operation time are prone to venous thromboembolism after surgery.
关键词	肺癌；静脉血栓栓塞；高危因素；D-二聚体
KeyWord	Lung cancer; Venous thromboembolism; Risk factors; D-dimer
基金项目
页码	23-26

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引用本文

崔晓海, 党国信, 孙彤宇. 肺癌术后患者并发静脉血栓栓塞危险因素分析 [J]. 国际临床研究杂志. 2026; 10; (3). 23 - 26.

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