International Journal of Clinical Research

Objective To explore the diagnostic value of low-frequency combined with high-frequency ultrasound in early liver cirrhosis of chronic hepatitis B (CHB). Methods A total of 90 CHB patients (from July 2024 to July 2025) admitted to our hospital were selected. All patients underwent low-frequency ultrasound, high-frequency ultrasound, and combined low-frequency and high-frequency ultrasound examinations. Liver biopsy was used as the gold standard, and the patients were divided into the liver cirrhosis group (42 cases) and the non-liver cirrhosis group (48 cases). The diagnostic efficacy and related ultrasound indicators of the three examination methods were compared. Results The diagnostic efficacy indicators such as sensitivity, specificity, and accuracy of the combined examination were significantly higher than those of the two ultrasound examinations alone (P < 0.05); the diameters of the portal vein and splenic vein in the liver cirrhosis group were larger than those in the non-liver cirrhosis group, and the blood flow velocity was lower (P < 0.05). Conclusion Low-frequency combined with high-frequency ultrasound can complement each other's advantages, improve the accuracy of diagnosing early liver cirrhosis in CHB, and is a reliable non-invasive imaging method.

Chronic hepatitis B; Early liver cirrhosis; Low-frequency ultrasound; High-frequency ultrasound; Diagnostic value