老年急性心梗患者PCI术后并发焦虑情绪的预测模型构建

Development of a prediction model for anxiety in elderly patients with acute myocardial infarction after percutaneous coronary intervention

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2026, 53(1)
作者
作者单位

新乡市第一人民医院 心血管内科

摘要
【摘要】 目的 基于生物-心理-社会医学模式,系统探讨影响老年急性心肌梗死(acute myocardial infarction, AMI)患者经皮冠状动脉介入治疗(percutaneous coronary intervention, PCI)术后并发焦虑情绪的心理与社会核心因素,并构建个体化预测模型。方法 选取2023年1月至2025年1月于新乡市第一人民医院行PCI治疗的老年AMI患者120例,根据术后3个月医院焦虑抑郁量表-焦虑分量表评分分为焦虑组(n=32)和非焦虑组(n=88)。收集社会人口学、临床指标、手术特征及患者报告结局,单因素分析和多因素Logistic回归筛选独立预测因子,构建列线图预测模型并验证。结果 多因素回归分析显示,独居(OR=3.371,95%CI:1.188-9.563)、Killip分级≥II级(OR=2.970,95%CI:1.015-8.694)、N-末端B型利钠肽原升高(OR=1.114,95%CI:1.038-1.195/100 pg/mL)、匹兹堡睡眠质量指数>7分(OR=5.951,95%CI:2.165-16.361)和疼痛数字评分法评分升高(OR=1.799,95%CI:1.277-2.535/分)是术后焦虑的独立预测因素。列线图校正后C指数为0.851,校准度理想。结论 本研究构建的预测模型能有效识别老年AMI患者PCI术后焦虑高风险人群,为早期心理干预提供量化依据。
Abstract
[Abstract] Objective: To systematically investigate the core psychosocial factors influencing the development of anxiety in elderly patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) based on the bio-psycho-social model, and to develop a personalized prediction model. Methods: A total of 120 elderly AMI patients who underwent PCI at Xinxiang First People's Hospital between January 2023 and January 2025 were enrolled. Based on Hospital Anxiety and Depression Scale-Anxiety subscale scores at 3 months post-PCI, participants were categorized into an anxiety group (n=32) and a non-anxiety group (n=88). Sociodemographic, clinical, procedural, and patient-reported outcomes were collected. Independent predictors were identified through univariate and multivariate logistic regression, followed by construction and validation of a nomogram prediction model. Results: Multivariate analysis revealed independent predictors: living alone (OR=3.371, 95%CI: 1.188-9.563), Killip class ≥II (OR=2.970, 95%CI: 1.015-8.694), elevated N-terminal pro-B-type natriuretic peptide (OR=1.114, 95%CI: 1.038-1.195 per 100 pg/mL), Pittsburgh Sleep Quality Index >7 (OR=5.951, 95%CI: 2.165-16.361), and higher Numeric Rating Scale score (OR=1.799, 95%CI: 1.277-2.535 per point). The nomogram achieved a corrected C-index of 0.851 with excellent calibration. Conclusion: The developed model effectively identifies elderly AMI patients at high risk for post-PCI anxiety, providing a quantitative tool for early psychological intervention.
关键词
【关键词】 急性心肌梗死;经皮冠状动脉介入治疗;焦虑;预测模型;列线图
KeyWord
[Keywords] acute myocardial infarction; percutaneous coronary intervention; anxiety; prediction model; nomogram
基金项目
页码 202-205
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牛玉玉. 老年急性心梗患者PCI术后并发焦虑情绪的预测模型构建 [J]. 国际精神病学杂志. 2026; 53; (1). 202 - 205.

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