Journal of International Psychiatry

[Abstract] Objective To explore the impact of pregnancy combined with schizophrenia on maternal and infant outcomes. Methods Forty cases of pregnancy complicated with schizophrenia from January 2020 to January 2023 at Xuanwu Hospital of Capital Medical University were selected as the study subjects. Forty normal pregnant women who were paired with gender and age during the same period were included, and they were divided into the observation group and the control group, respectively. The maternal and infant outcomes between two groups of pregnant women were recorded and compared. Results The incidence of pregnancy diabetes, abortion, premature rupture of membranes in the observation group was significantly higher than that in the control group (P<0.05). There was no statistically significant difference in the incidence of gestational hypertension and postpartum hemorrhage between the two groups (P>0.05). The incidence of premature birth, low birth weight, congenital defects, and asphyxia in the observation group was significantly higher than that in the control group (P<0.05). There was no statistically significant difference between the two groups of macrosomia (P>0.05). Conclusion Pregnancy with schizophrenia increases the incidence of pregnancy and perinatal complications such as diabetes, premature rupture of membranes, and other adverse outcomes such as premature delivery and low birth weight.

Key words Pregnancy; Schizophrenia; Maternal and Infant Outcomes; Complications