Journal of International Psychiatry

Objective To explore the traditional Chinese syndrome standardization of schizophrenia. Methods 640 patients with schizophrenia enrolled from Hunan Brain Hospital were investigated. The information collected were statistic analyzed. We aimed to obtain the common Chinese syndromes, corresponding syndrome elements, Chinese syndrome-related clinical symptoms and signs of schizophrenia via expert questionnaire combined with multivariate statistical analysis. Results Among the 640 schizophrenia patients, the common (rate＞5%) Chinese syndromes are as follows: 74 patients with heart-spleen deficiency syndrome (11.56%), 60 patients with yin-deficiency and fire-hyperactivity syndrome (9.38%), 59 patients with internal disturbance of pyrophlegm syndrome (9.22%), 58 patients with liver qi invading spleen syndrome (9.06%), 55 patients with spleen and kidney yang deficiency syndrome (8.59%), 53 patients with phlegm-qi stagnation syndrome (8.28%), and 43 patients with effulgent liver-gallbladder fire syndrome (6.72%). There are good distinctions in each Chinese syndrome of coated tongue and pulse condition. Conclusion The identification of common Chinese syndrome-related clinical symptoms and signs from schizophrenia patients provides an objective evidence for the draft of Chinese syndrome scale of schizophrenia.

Schizophrenia; Traditional Chinese medicine; Chinese syndrome; Standardization