Journal of International Psychiatry

[Abstract]Objective:To study the application effect and its influence on quality of life of the comprehensive intervention in patients with schizophrenia.Methods:The subjects were 120 schizophrenic patients in psychiatric first peoples Hospital of Chuzhou city between January 2013 to December 2014,all the patients were cured by systemic treatment., random number.randomly divided into control group and observation group,60 cases in each group.the control group were given routine guidance and follow-up after discharge,the observation group were given comprehensive intervention, intervention continued for 2 years.compared two groups of the positive and negative symptom scale (PANSS), social function rating scale (SDSS), family function rating scale (FAD) and quality of life questionnaire (GQOLI) score before intervention and 2 years after intervention.Results: after the intervention, the observation group of negative and positive symptoms and PANSS scores were significantly lower than the control group (P<0.01), the observation group of the SDSS and FAD scores were significantly lower than the control group (P<0.01), the observation group of the physical function, psychological function, social function and overall quality of life scores were significantly higher than the control group (P<0.01). Conclusion:the comprehensive intervention can improve the symptoms of schizophrenia after discharge, improvePatients social function and quality of life, to enhance the family happiness, it is worth in clinical promotion.

[Key words] comprehensive intervention; schizophrenia; application effect; quality of life