Journal of International Psychiatry

[Abstract]Objective:To discuss the impact of quality of life in patients with cognition impairment after cerebral stroke treated with donepezil and cognitive function training.Methods:68 patients with cognition impairment after cerebral stroke from June 2014 to January 2016 were randomly selected and divided into 34 patients of them treated with donepezil only were taken as control group,while the other 34 patients treated with donepezil combined cognitive function training were taken as research group.Compared the scores of MMSE, MoCA and ADL before and after treatments with two groups,evaluated the clinical effects on two groups.Compared the score of SS-QOL before and after treatments in 6 months with two groups.Results: The total effective rate was 88.24% in research group,while that in control group was 67.65%( P＜0.05);The scores of MMSE and MoCA were (25.79±5.21) and (24.87±4.96) in reseaerch group after treatments ,which were higher than that in control group(P＜0.05);The score of ADL was (28.48±5.06) in reseaerch group after treatments,which was lower than that in control group(P＜0.05).The score of SS-QOL was (184.76±31.78) in reseaerch group after treatments,which was higher than that in control group(P＜0.05).Conclusion:Patients with cognition impairment after cerebral stroke treated with donepezil in treatments of cognitive function training cam improve cognitive function, activity of daily living and quality of life,which is worthy clinical use.

[Keywords]Cognition impairment;Cerebral stroke;Donepezil;Cognitive function training;Quality of life