一种新型掩苦制剂针对清热类中药的效果

The effect of a new type of bitter masking preparation on traditional Chinese medicine for clearing heat

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DOI 10.12208/j.ircm.20250027
刊名
International Research in Chinese Medicine
年,卷(期) 2025, 5(3)
作者
作者单位

郑州工业应用技术学院医学院 河南郑州

摘要
目的 探讨分析新型掩苦制剂对于清热类中药的效果,为其临床广泛使用提供参考依据。方法选取2023年9月-2023年10月招募收集的60名在校大学生作为志愿者,随机分为对照组和试验组各30例。两组均口服极苦清热类中药。在此基础上对照组给予常规抑苦制剂(中药伴侣),试验组给予新型掩味制剂。对比两组应用掩味制剂的苦度效果情况,分析试验组和对照组掩味制剂使用前后的效果分析,并采取问卷调查分析临床效果满意度、苦度评价表、焦虑抑郁评价。结果 试验组的总体满意度显著高于对照组,差异有统计学意义(P<0.05)。试验组和对照组前后使用抑苦制剂前后对比效果具有差异性,且试验组水平均显著高于对照组,差异有统计学意义(P<0.05)。试验组的焦虑评分、不良反应均显著低于对照组,差异有统计学意义(P<0.05)。试验组的临床疗效、苦度降低值、作用持续时间、达峰时间显著高于对照组,差异有统计学意义(P<0.05)。结论 新型掩味制剂对于清热类中药的临床效果较为显著,可大幅度降低中药苦度,提升口感,具有广泛应用价值。
Abstract
Objective To explore and analyze the effect of new bitter masking preparation on heat clearing traditional Chinese medicine, and provide reference for its wide clinical use. Methods 60 college students recruited from September 2023 to October 2023 were selected as volunteers and randomly divided into control group and experimental group, with 30 cases in each group. Both groups were treated with extremely bitter heat clearing herbs. On this basis, the control group was given conventional anti bitterness preparation (traditional Chinese medicine partner), and the experimental group was given new bitter masking preparation. The bitterness effect of the two groups was compared, and the effect of the experimental group and the control group before and after the use of the bitter masking agent was analyzed. The clinical effect satisfaction, bitterness evaluation form, anxiety and depression evaluation were analyzed by questionnaire survey. Results The overall satisfaction of the experimental group was significantly higher than that of the control group, the difference was statistically significant (P<0.05). The experimental group and the control group were significantly higher than the control group before and after the use of anti bitterness preparation, and the difference was statistically significant (P<0.05). The anxiety score and adverse reactions of the experimental group were significantly lower than those of the control group, the difference was statistically significant (P<0.05). The clinical efficacy, bitterness reduction value, duration of action and peak time of the experimental group were significantly higher than those of the control group, and the differences were statistically significant (P<0.05). Conclusion The new bitter masking preparation has a significant clinical effect on heat clearing traditional Chinese medicine, which can significantly reduce the bitterness of traditional Chinese medicine and improve the taste, and has a wide application value.
关键词
掩味制剂;清热中药;满意度;苦度评价
KeyWord
Bitter masking preparation; Traditional Chinese medicine for clearing heat; Satisfaction; Bitterness evaluation
基金项目
页码 7-13
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关鑫, 韩东辰, 刘晨煜, 王英, 张佳明, 张景亮. 一种新型掩苦制剂针对清热类中药的效果 [J]. 国际中医药研究. 2025; 5; (3). 7 - 13.

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