International Medical Research Frontier

Objective To evaluate the clinical efficacy of Niuhuang Shedan Chuanbei Drop Pill combined with ambroxol hydrochloride and clenbuterol hydrochloride oral solution for the treatment of cough and phlegm. Methods A total of 96 patients were included in the study and randomly assigned to a control group and a treatment group. The control group was treated with ambroxol hydrochloride and clenbuterol hydrochloride oral solution oral solution, while the treatment group was given Niuhuang Shedan Chuanbei Drop Pill combined with ambroxol hydrochloride and clenbuterol hydrochloride oral solution oral solution for a treatment period of 7 days. Traditional Chinese medicine (TCM) syndrome evaluation indicators before and after treatment were used to assess the clinical effects. In addition, the FEV₁/FVC and FEV₁/pred ratios of pulmonary function were also used to evaluate the clinical efficacy. Results After treatment, the TCM syndrome scores and their sums decreased significantly in both groups; the total clinical effective rates were 66.7% and 95.8% respectively, and the difference was statistically significant (p<0.01) by chi-square test analysis; compared to the control group, the treatment group showed significant improvements in the primary and secondary symptoms of TCM syndrome (p<0.01); the FEV₁/FVC and FEV₁/pred ratios of pulmonary function also significantly increased (p<0.05 or p<0.01). Conclusion Niuhuang Shedan Chuanbei Drop Pill combined with ambroxol hydrochloride and clenbuterol hydrochloride oral solution shows good clinical efficacy in treating cough and phlegm.

Niuhuang Shedan Chuanbei drop pill; Ambroxol hydrochloride and clenbuterol hydrochloride oral solution; Relieve cough and reduce phlegm; Clinical assessment